OBJECTIVE To synthesize the presumable bone-targeting nonsteroidal anti-inflammatory agents.METHODS L-Asp6 was prepared by aspartic acid which was protected.

目的合成可能具有骨靶向的非甾体抗炎药。

PASP-PEG block structure copolymer,comb shaped PASP-PEG block structure copolymer,aspartic acid and glycine,glutamic acid or propalanine copolymer are prepared.

还可以对聚天冬氨的侧链进行改,引入烷或烯、应活高的氨酯、磺等功能,使其得到更广泛的应用。

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

由转氨作用形成的一种氨，谷氨的氨被转移到草酰乙中。

The tripeptide Arginyl-Glycyl-Aspartic acid (RGD) is a common cell recognition site of many adhesive proteins contained in extracellular matrices and in the blood .

RGD三肽（精氨酰-甘氨酰-天冬氨）序列是细胞外质及血液中的许多粘附蛋白共有的细胞识别位点。